Mesothelioma Cancer

A vaccine against mesothelioma, a cancerassociated with exposure to asbestos, has shown early promise in its first clinical trial.

The experimental vaccine is an example ofdendritic cell (DC)-based immunotherapy, in which the body’s own immune system is harnessed to target and destroy cancer cells.

In the vaccine, a sample of the patient’s ‘dendritic’ immune cells are mixed with proteins taken from their tumour.

When implanted back into the patient, these cells can then activate other elements of the patient’s immune system, known as T-cells, and encourage them to attack and destroy the tumour.

Researchers at Erasmus Medical Center in The Netherlands have previously shown that DC vaccinesbring about an anti-tumour response in mice and decided to test the technique in humans.

They enrolled ten people who had recently been diagnosed with a form of mesothelioma called ‘malignant pleural’ mesothelioma, and who had been previously treated with chemotherapy.

The team took a sample of dendritic cells from each patient’s blood, and exposed them to proteins from their tumours.

The dendritic cell samples were also exposed to a ‘marker’ protein called keyhole limpet hemocyanin (KLH).

Patients then received three injections of their ‘activated’ dendritic cells over a two-week period.

Publishing their findings in the American Journal of Respiratory and Critical Care Medicine, the researchers revealed that all ten patients had antibodies to the KLH marker in their blood, confirming that the vaccines had brought about an immune response.

Further tests on four of the patients’ tumours revealed that three of the tumours had got smaller, although this could not be conclusively or directly linked to the vaccine…. Read more…

Suzette Allinger, 56, remembers the day in July of 2008 when she was diagnosed with breast cancer.

Allinger, of the Creve Coeur area, had gone to see Dr. Alan Londe, a general surgeon, after she’d had severe breast pain. His diagnosis of cancer couldn’t have come at a worst time.

Allinger, whose husband of 20 years, Justin, had been laid off from retail management the year before. They had no private health insurance.

But with a part-time job in the cosmetics field, she couldn’t qualify for Missouri Health Net, Medicaid or other government programs.

“As I was crying a bucket of tears, Dr. Londe told me to take a deep breath and talk to Gateway to Hope,” she said.

That suggestion changed her life.

Londe is one of many doctors and other medical providers who donate services and products to the non-profit Gateway to Hope.

Based in Creve Coeur, the organization arranges no-cost comprehensive medical care for breast cancer patients who lack sufficient financial resources or insurance, but are ineligible for assistance through state and federal programs.

It was founded in 2005 by Dr. David Caplin, of Frontenac, a plastic/reconstructive surgeon, and Dr. Marlys Schuh of Creve Coeur, an oncology breast surgeon.

Caplin recalls a patient who was the catalyst for establishing the organization.

“This young woman was the sole breadwinner for her kids and disabled husband. She made enough so she wasn’t qualified for Medicaid but couldn’t afford insurance,” he said…. Read more…

ATLANTA – The American Cancer Society is urging doctors to make clearer to men that the test used to screen for prostate cancer has limits and may lead to unnecessary treatments that do more harm than good.

The cancer society has not recommended routine screening for most men since the mid-1990s, and that is not changing. But its new advice goes farther to warn of the limitations of the PSA blood test that millions of American men get now. It also says digital rectal exams should be an option rather than part of a standard screening.

The new advice is the latest pushback from routine screening to hunt for early cancers. Last year, a government task force said most women don’t need mammograms in their 40s and a doctors group said most women in their 20s don’t need annual Pap tests…. Read more…

Colorectal cancer is the second leading cancer killer of men and women in the U.S., and March is awareness month for this disease.

The American Cancer Society says colorectal cancer claims more lives than either breast or prostate cancer. Each year there are about 150,000 new cases of colorectal cancer, and 50,000 people lose their lives to the disease.

Colorectal cancer occurs when tumors grow in the colon or rectum, which make up the large intestine. Symptoms might include blood in the stool, general fatigue or the inability to go the bathroom.

The scary thing is that colorectal cancer often shows no symptoms at all, until it`s too late.

“Screening helps you catch it early which is why recommendations start at age 50. It`s kind of a double bonus because if you catch it early, there may not be recommendations for anything beyond surgery and you can avoid chemo and radiation,” said radiation oncologist Dr. John Watkins.

Caught early enough, the small tumors, called polyps, can even be removed during a colonoscopy, but if the symptoms are ignored, or routine screenings are skipped, the results can be serious…. Read more…

The Mesothelioma Victims Center was created out of frustration as to what to do after a diagnosis of a rare form of cancer called mesothelioma. Mesothelioma is caused by exposure to asbestos. One third of all US mesothelioma victims served in the US Navy. The Mesothelioma Victims Center says, “most importantly, in 2010, we want to make sure a mesothelioma cancer victim, or their family gets the names of the actual best mesothelioma law firms, or attorneys in the US. Tragically looking for a law firm on the Internet, or in the phone book will frequently not deliver this result.” The group says, “many, to maybe most of the law firms advertising on the Internet, or on radio/TV for mesothelioma cancer victims sell the cases to real mersothelioma law firms. They do not do the trial work themselves. We intend to cut out these middlemen out in 2010-its wrong & misleading.” If a mesothelioma cancer victim, or their family wants the names of the top actual mesothelioma law firms in the US, they can call the Mesothelioma Victims Center anytime at 866-714-6466, or contact the group via its web site at Http://MesotheliomaVictimsCenter.Com

(Vocus/PRWEB ) March 1, 2010 — The Mesothelioma Victims Center is all about creating the absolute best free service for a US victim, or family members of a victim of a rare form of cancer called mesothelioma. As part of its mesothelioma victims initiative for 2010, the group intends to cut middlemen law firms, that sell mesothelioma victims to actual mesothelioma trial attorneys, out of the mesothelioma victims equation. The group says, “you hear, or see a compelling law firm advertising spot on radio, TV, phone book offering help for a mesothelioma victim. There is just one really important disclaimer-many forget to say, & we are going to sell your Dad, or Mom to a real mesothelioma law firm, we are not going to do the trial work—-and we make tons of money doing this.” The group says, ” for many law firms a mesothelioma victim is something you sell to make money. We say-call us, and we will give you the names of some of the best actual mesothelioma law firms in the US, and no family members Dad, or Mom gets sold to the highest bidder law firm.” If a mesothelioma cancer victim, or their family members want the names of some of the best mesothelioma law firms in the United States, call the Mesothelioma Victims Center anytime at 866-714-6466, or contact the group via its web site atHttp://MesotheliomaVictimsCenter.Com

Who Can Get Mesothelioma:

One third of all U.S. mesothelioma victims served in the U.S. Navy between 1930 & 1980.

U.S. Navy or ship yard workers who worked in the following shipyards should be tested for asbestosis: California : U.S. Naval Shipyard at Mare Island, U.S. Naval Shipyard at San Francisco, and the U.S. Naval Shipyard at San Francisco Bay. The San Francisco Naval Shipyard was also known as Hunters Point Naval Shipyard and Treasure Island Naval Station Hunters Point Annex, & Long Beach California. Washington State had the Todd Shipyards & the Puget Sound Naval Shipyard in Bremerton, WA. On the East Coast there is Norfolk & Portsmouth Naval Shipyards.

Mesothelioma cancer is a result of asbestos exposure. Individuals who worked in mines, oil refineries, ship yard workers, carpenters, plumbers, boiler room technicians construction demolition, auto brake repair professionals, HVAC technicians, and others who were exposed to asbestos can get mesothelioma….. Read more…

A growing number of women with cancer in one breast choose to have their other, healthy breast removed in hopes it will prevent a second cancer. But new research finds that elective surgery improved survival in only a small group of women — those who are under 50 and are in the early stages of a type of breast cancer known as estrogen receptor-negative cancer…. Read more…

THURSDAY, Feb. 25 (HealthDay News) — Endometrial cancer patients at medium to high risk for cancer recurrence are more likely to survive if both the pelvic lymph nodes and para-aortic lymph nodes are removed, rather than just the pelvic lymph nodes, say Japanese researchers.

The para-aortic lymph nodes, which are located in front of the lumbar vertebral bodies near the aorta, receive drainage from the lower gastrointestinal tract and the pelvic organs, according to a news release about the study.

The study included 671 women with endometrial cancer who had pelvic lymph nodes removed or both pelvic and para-aortic lymph nodes removed. Women at medium or high risk for cancer recurrence were offered additional treatment in the form of chemotherapy or radiotherapy…. Read more…

Clinical trial launched to test new treatment technique for bowel cancer

Cancer Research UK this week launches a new trial for patients with bowel cancer that has spread to the liver to see whether a newradiotherapy treatment technique is more effective than standard chemotherapy.

Researchers at trial centres across the UK and coordinated at Oxford University will test a new treatment called Radio-embolisation, a form of internal radiotherapy that uses the tumour’s blood supply to target multiple sites of disease within the liver. They will combine this new treatment with standard chemotherapy in patients recently diagnosed with bowel cancerthat has spread to the liver.

The first patient will start the treatment this week at the Royal Surrey County Hospital in Guildford.

Despite major advances in treating advanced bowel cancer, the number of patients who survive beyond five years remains disappointingly low – less than 10 per cent…. Read more…

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